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半面的隐藏负担:对非运动症状的系统审查

Miriam Carvalho Soares¹, Jacy Bezerra Parmera², Pedro Augusto Sampaio Rocha-Filho³

¹Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco (UFPE), Recife, Brazil.

Movement disorders clinical practice

|March 5, 2026

概括

半面涉到不仅仅是面部抽,包括显著的疼痛,情绪和睡眠问题. 解决这些非运动性症状是改善患者生活质量的关键.

科学领域:

神经学神经学
临床医学临床医学

背景情况:

半面 (Hemifacial Spasm,简称HFS) 是一种慢性神经疾病,导致非自愿的面部肌肉收缩.
除了运动症状之外,HFS还表现出经常被忽视的非运动症状,影响患者的生活质量.

研究的目的:

系统地审查在半面 (HFS) 中非运动表现的流行率和临床相关性.

主要方法:

在PubMed,Cochrane和EMBASE的系统文献搜索到2025年6月.
包括横截面,队列,病例控制和病例系列研究,报告HFS中的疼痛,精神病或睡眠问题.
使用乔安娜·布里格斯研究所工具评估的偏见风险.

主要成果:

分析了22项研究,揭示了普遍存在的非运动症状:头痛 (24.2%-60%),面部疼痛 (33.3%),抑郁 (5.7%-29%),焦虑 (9.1%-19.5%) 和失眠 (多达3次对照).
毒素 (BoNT) 治疗在减少疼痛,焦虑和抑郁症状方面显示出好处.
非运动症状显著影响患者的幸福感.

结论:

半面是一种多维疾病,具有相当大的非运动负担.
识别和管理疼痛,精神病和睡眠症状对于有效的HFS治疗和患者福祉至关重要.

关键词:

抑郁抑郁症抑郁症抑郁症是一种面部疼痛面部疼痛头痛是一种头痛.半面部面部失眠是因为失眠.

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