佩利诺1-mTOR/S6K1信号轴是多囊性病发展的关键病原体

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Updated: Mar 7, 2026

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium

Published on: September 1, 2015

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Suhyeon Kim1, Min-Hee Kim1, Bo-Kyoung Ko1

  • 1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.

Cell death & disease
|March 5, 2026
PubMed
概括

E3酶Pellino1 (Peli1) 通过促进炎症和囊生长来驱动多囊病 (PKD) 的进展. 准Peli1可能为ADPKD和ccRCC等脏疾病提供新的治疗策略.

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