通过使用SHIME体外模拟器使用,豆和乳清蛋白进行肠道微生物组调节
Irene Franciosa1, Gabriele Castelnuovo2, Carolina Cantele1
1Department of Agricultural, Forest and Food Sciences, University of Torino, Torino, Italy.
NPJ science of food
|March 5, 2026
概括
板蛋白摄入量对肠道细菌和有益化合物产生积极影响,类似于豆和乳清蛋白. 这种可持续的昆虫蛋白对人类肠道微生物组没有有害影响.
科学领域:
- 微生物学和营养科学 微生物学和营养科学
- 肠道微生物组研究研究
- 可持续的食物来源 可持续的食物来源
背景情况:
- 昆虫 (食用昆虫) 正在作为环保蛋白质来源获得吸引力.
- (cricket) 蛋白质是一种可持续的替代品,但其对肠道微生物群的影响需要研究.
- 了解蛋白质来源对肠道健康的影响对于饮食建议至关重要.
研究的目的:
- 为了研究孤立的豆,乳清和球蛋白对人类肠道微生物群的影响.
- 为了比较植物,动物和昆虫蛋白对微生物组成和功能的影响.
- 在模拟的肠道环境中评估板蛋白的安全性和潜在益处.
主要方法:
- 使用人类肠道微生物生态系统模拟器 (SHIME®) 用单个捐赠者的便样本.
- 管理的孤立的豆类,乳清和球蛋白质.
- 进行了基因组分析,以评估微生物变化和功能性基因表达.
主要成果:
- 板球蛋白摄入量与有益细菌 (Bifidobacterium,Lactobacillus) 和短链脂肪酸 (SCFA) 的增加相关.
- 豆蛋白摄入与Faecalibacterium和Slackia有关,并增加了氨酸降解基因.
- 乳清蛋白摄入量显示与Butyricimonas和Lactobacillus有关联.
结论:
- 每个蛋白质来源 (豆类,乳清,) 都会独特地影响肠道微生物群.
- 板的蛋白质摄入量显示出潜在的益处,促进有益的种类和SCFA生产.
- 在肠道微生物组的影响方面,板蛋白似乎是安全的,与植物和动物蛋白相比.
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