相关实验视频

Updated: Mar 7, 2026

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
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Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

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通过结构导向工程来改变豆类培养素FRIL的碳水化合物结合特异性

Yo-Min Liu1, Hong Thuy Vy Nguyen1, Xiaorui Chen1

  • 1Genomics Research Center, Academia Sinica, Taipei, Taiwan.

Nature communications
|March 5, 2026
PubMed
概括

豆类中含有的FRIL,具有抗病毒性质,并结合复杂的N-甘氨酸. 研究人员发现,碳水化合物识别域 (CRD) 中的循环B决定了特异性,区分了复杂和高曼诺斯N-甘氨酸.

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相关概念视频

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Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
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Conserved Binding Sites01:49

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Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
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