在急性呼吸衰竭患者中确定喉胀和吸气之间的关联
Lucas Dm1,2, Peterson R3, Rieck J3
1Department of Otolaryngology, Boston Medical Center, Boston, MA, USA. Devin.lucas@bmc.org.
概括
喉水腫,尤其是在aryepiglottic上,在急性呼吸衰竭的幸存者中顯著增加吸入風險. 患者的软弱也独立地提高了吸血风险,但与效应没有相互作用.
科学领域:
- 复苏和重症监护医学 复苏和重症监护医学
- 耳鼻喉科 - 头部和部手术
- 吞障碍和吞失调的情况
背景情况:
- 在急性呼吸衰竭 (ARF) 患者中,三分之一的患者在长时间的输管治疗 (>48小时) 后经历了吸气.
- 喉 edem 是一个潜在的可修改的风险因素,用于 post-extubation 吸收.
- 了解喉水的解剖分布和严重程度对于评估吸入风险至关重要.
研究的目的:
- 在ARF幸存者中描述喉 edem 的解剖分布.
- 为了将喉 edem 的严重程度与 extubation 后吸入的风险相关联.
- 调查患者的软弱是否会改变喉胀和吸气风险之间的关系.
主要方法:
- 一项用灵活内镜评估吞 (FEES) 视频的病例控制研究,来自120名ARF幸存者 (60名吸气者,60名非吸气者).
- 在八个位置使用修订的帕特森胀量表 (RPES) 评估了喉胀.
- 患者的软弱被评估使用咳流量峰值和喉介质化;逻辑回归模型分析了关联.
主要成果:
- 阿里皮格洛特折叠胀是排泄后吸收最强的解剖学预测因素 (aOR=5.74).
- 患者的软弱独立增加了吸血风险 (aOR=3.93).
- 在预测吸气风险时,喉水和弱点之间没有发现显著的相互作用.
结论:
- 喉 edem,特别是 aryepiglottic edem,是ARF幸存者的吸收的一个显著的危险因素.
- 患者的软弱是吸引力的独立风险因素.
- 这些发现支持进一步研究喉胀在志向和发展有针对性的干预措施中的作用.
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