在宫癌细胞模型中,R2TP复合物稳定了E7以驱动人类乳头瘤病毒介导的病原发生

Mahaiwon Shadang1, Aruna Arumugam1,2, Dhiraj Kumar Singh1

  • 1Department of Biochemistry, All India Institute of Medical Sciences, Delhi, India.

Virology journal
|March 5, 2026
PubMed
概括

人类乳头瘤病毒E7蛋白与R2TP复合体子单元PIH1D1相互作用,这对宫癌的进展至关重要. 这种由E7酸化调节的相互作用促进瘤生长和迁移,表明PIH1D1是治疗点.

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