结核病的肌肉骨后果
Filippo Migliorini1,2,3, Francesco Simeone4, Luise Schäfer5
1Department of Trauma and Reconstructive Surgery, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Street 40, 06097, Halle (Saale), Germany. filippo.migliorini@uk-halle.de.
结肠病会影响骨,肌肉和关节,导致骨质疏松症和肉症等问题. 早期识别和多学科方法对于管理这些系统性肌肉骨影响至关重要.
科学领域:
- 胃肠道学和免疫学
- 肌肉骨医学 肌肉骨医学
- 系统性自身免疫性疾病
背景情况:
- 结肠病越来越多地被认为是一种超出胃肠道的全身性疾病.
- 肌肉骨的表现,包括骨脆弱性,肉症和关节病,往往被忽视.
- 这些后果影响了所有年龄段的个人,从儿童到老年人.
研究的目的:
- 批判性地审查将质敏感性与肌肉骨衰退联系在一起的病理生理学.
- 整合关于病对骨,肌肉和关节健康的影响的发现.
- 突出这些系统性后果的诊断不足和治疗不足.
主要方法:
- 现有文献的叙述性审查.
- 在儿科,成人和老年人群中整合发现.
- 探索涉及营养,炎症,免疫和微生物群因素的多方面的病理生理学.
主要成果:
- 结肠病与骨折风险增加,早期出现的骨质疏松症和肉症有关.
- 慢性炎症,营养缺乏,免疫失调和肠道失调有助于肌肉骨衰退.
- 肌肉骨功能障碍甚至可以发生在无症状的个体或潜在患有胰腺疾病的人身上.
结论:
- 结肠病给肌肉骨系统带来了相当大的,往往未被认可的负担.
- 一种多学科的管理方法是必不可少的,包括质排除,营养支持和康复.
- 在胃肠病学和肌肉骨医学中,需要提高临床意识和对管理优先事项的重新评估.
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