未知的初级黑色素瘤呈肠道阻塞:一个诊断挑战
Alexandru Cosmin Palcău1, Octavian Andronic, Alexandra Bolocan
1Department of General Surgery, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; octavian.andronic@umfcd.ro.
概括
转移性黑色素瘤可以呈现为小肠阻塞或肠,即使没有已知的初级病变. 手术切除是孤立胃肠道转移的关键,免疫组织化学有助于诊断.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 皮肤病理学 皮肤病理学
背景情况:
- 胃肠道 (GI) 转移性黑色素瘤通常无症状,通常影响小肠.
- 成年人内肠接是罕见的,经常是由潜在的瘤引起的.
- 由于缺乏可识别的原发性病变,未知原发性黑色素瘤 (MUP) 存在诊断挑战.
研究的目的:
- 为了呈现一个成年人肠静脉分泌的情况,继发于未知的初级转移性黑色素瘤.
- 突出胃肠道黑色素瘤的诊断和治疗方面的考虑.
主要方法:
- 一个64岁的女性患有亚急性肠道阻塞的病例报告.
- 经过细分肠切除术后通过组织病理学和免疫组织化学 (S100,Melan-A,PRAME,CD117) 证实了诊断.
- 全身检查,排除原发性黑色素瘤病变.
主要成果:
- 由性内体质引起的内肠被手术切除.
- 组织病理学证实了转移性黑色素瘤;没有发现一次性病变.
- 患者在术后有了良好的后果.
结论:
- 在成年人肠内瘤和小肠瘤中,特别是MUP中,应考虑转移性黑色素瘤.
- 手术切除是症状隔离的胃肠道转移的主要治疗方法.
- 免疫组织化学对于诊断至关重要,但不能区分小肠中的初级和转移性病变.
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