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含有伊米达索皮里迪尼 (IP) 单元的宏环显示增强的被动细胞透性

Bo Li1, Joshua Parker1, Skyler Briggs2

  • 1Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, 120 Scripps Way, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|March 6, 2026
PubMed
概括

嵌入伊米达索皮里迪尼 (IP+) 增强了宏环 (MP) 进入细胞的速度,使细胞质进入细胞内蛋白质的目标. 这一策略克服了薄膜透性,导致生物活性抑制剂用于治疗开发.

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