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Updated: Mar 7, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

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隆尼达胺通过减少SREBP1和抑制MAPK通路来改善MASH

Yuhan Chen1, Feiyan Pan2, Lusheng Tang3

  • 1Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou 310014, China.

Acta biochimica et biophysica Sinica
|March 6, 2026
PubMed
概括

隆尼达胺 (LND) 显示了对代谢功能障碍相关的脂肪肝炎 (MASH) 的治疗潜力. 它通过抑制MAPK通路并与SREBP1.1相互作用来减少炎症并改善脂质代谢.

关键词:
肝炎是一种肝炎.脂质新陈代谢 脂质新陈代谢洛尼达胺 (Lonidamine) 是一种一种与代谢功能障碍相关的脂肪肝炎.固醇调节元素结合蛋白 1 1

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