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Updated: Mar 7, 2026

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DCAF13通过RRS1-调节的核糖体生物发生来保护造血干细胞

Mengke Li1, Yuxin Wu2, Shuai Zhou2

  • 1Institute of Hematology, Henan Key Laboratory of Stem Cell Differentiation and Modification, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 6, 2026
PubMed
概括

DCAF13稳定RRS1,这是一个关键的核糖体生物发生因子,以维持血造干细胞 (HSC) 功能. 它的缺乏导致HSC枯竭和造血失败,揭示了血液生产的关键DCAF13-RRS1轴.

关键词:
在 DCAF13 中使用.在HSC上,HSC是高质量的.在P53中,P53是P53RRS1 RRS1 的意思是什么?核糖体生物发生的生物生成

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