肌肉功能缺陷的变化以及2型糖尿病的老年人中sarcopenic肥胖症的临床鉴定
Sharon Barak1,2, Roy Eldor3,4, Idit Dotan4,5
1Department of Nursing, School of Health Sciences, Ariel University, Ariel, Israel.
Frontiers in medicine
|March 6, 2026
概括
麻性肥胖 (SO) 影响了2型糖尿病 (T2D) 的72%的老年人,显示出显著的肌肉功能和身体组成障碍. 使用常规措施的新指数有效地预测了这一群体中的SO风险.
科学领域:
- 老年学是指老年学的学科.
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 肥胖症 (SO) 在老年人中越来越令人担忧,特别是那些患有2型糖尿病 (T2D) 的人,导致不良健康结果.
- SO评估通常涉及肌肉功能测试和身体组成分析,但患病率因方法而异,常规临床实施因时间限制而有限.
研究的目的:
- 根据既定的指导方针,评估社区居住的2型糖尿病老年人肌肉功能变化的患病率.
- 开发风险集群来预测SO概率.
- 创建一个基于常规临床测量的SO指数,以区分SO的可能性.
主要方法:
- 100名患有T2D的老年人接受了手握强度,膝盖伸展强度和椅子站测试的评估.
- 使用生物电阻分析测量身体成分; 确定相对于体重的尾瘦质量.
- 收集了临床数据,包括腰围,BMI,药物,代谢标志物和身体功能.
主要成果:
- 改变肌肉功能的患病率差异很大 (手握强度为1%,椅子站强度为92%).
- 在72%的参与者中存在SO,确定了三种严重程度集群:严重 (37%),中度 (32%) 和轻度 (31%).
- 通过使用腰围,BMI,药物计数,HbA1c和椅子站测试结果,开发了一种经过验证的SO风险指数 (AUC=0.87).
结论:
- 麻性肥胖症在患有T2D的老年人中非常普遍,其特点是显著的肌肉功能和身体组成缺陷.
- 尾肌瘦质量和下肢强度是SO严重性的关键驱动因素,而手握强度则限制了歧视力.
- 综合功能和身体组成评估对于管理T2D和SO的老年人至关重要.
相关概念视频
Disorders of the Skeletal Muscle
2.1K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.1K
Diabetes: Symptoms, Diagnosis, and Complications
2.6K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.6K


