COVID-19对酒精相关发病率和死亡率的影响:一项多中心研究
Abhinav K Rao1,2, Erica Paulos1, Nancy Crossley2
1Division of Internal Medicine, Trident Medical Center, North Charleston, SC, USA.
概括
随着COVID-19大流行,酒精相关疾病患者的病情恶化,死亡率和住院时间增加. 这项研究强调了饮酒障碍和COVID-19感染的复合风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19大流行与全国范围内的酒精消费增加有关.
- 与酒精有关的疾病是严重的公共卫生问题.
- 了解同时感染COVID-19对这些患者的影响至关重要.
研究的目的:
- 调查COVID-19对酒精相关疾病患者医院治疗结果的影响.
- 为了比较大流行前和大流行期间的结果.
- 分析COVID-19诊断对患者情绪和死亡率的具体影响.
主要方法:
- 使用了2018-2022年 (HCA南大西洋部门) 的非识别索赔数据.
- 包括患有酒精使用障碍或酒精相关疾病的成年患者 (>18岁).
- 在COVID-19前 (2018-2019) 和COVID-19 (2021-2022) 期间的比较结果 (停留时间,出院,死亡率).
主要成果:
- 在COVID-19期间,与COVID-19前相比,死亡率增加36%,家庭出院率下降2%,平均逗留时间 (LOS) 增加0.5天.
- 患有COVID-19和酒精相关疾病的患者的LOS时间长3天,出院的可能性降低60%,住院患者死亡率提高284%.
- 在26678名COVID-19期间入院患者中,有35%被诊断为COVID-19.
结论:
- COVID-19诊断显著恶化了酒精相关发病率患者的医院结果.
- 这些患者住院时间更长,出院次数减少,死亡率大幅上升.
- 这些发现强调了与酒精相关疾病的个体在与COVID-19同时感染时的高度脆弱性.
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