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益生菌对纤维肌痛患者心理问题的影响:系统性审查

Amin Nakhostin-Ansari¹, Negin Khosravipour¹, Sara Pedram Jafari¹

¹Department of Physical Medicine and Rehabilitation, Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran.

Annals of medicine and surgery (2012)

|March 6, 2026

概括

这次审查发现了关于益生菌缓解纤维肌痛症状的不一致的证据. 虽然一些研究表明对焦虑和抑郁有好处,但需要更多的研究来确认纤维肌痛患者的有效性和安全性.

科学领域:

胃肠病学胃肠病学
心理学心理学心理学
类风湿病学类风湿病学

背景情况:

纤维肌痛是一种复杂的慢性疾病,其特点是广泛的疼痛,疲劳和心理困扰.
目前对纤维肌痛的治疗选择有局限性,需要探索新的治疗方法.

研究的目的:

系统地审查益生菌对被诊断为纤维肌痛患者心理症状,疼痛和疲劳的影响.
评估益生菌补充剂作为辅助或独立治疗纤维肌痛的有效性和安全性.

主要方法:

在PubMed,Scopus和Web of Science上进行了系统的文献搜索,搜索到2025年1月19日之前发表的研究.
包括的研究比较了益生菌 (单独或与其他治疗结合) 与安慰剂或纤维肌痛患者的其他干预措施.
使用JBI批判性评估工具评估研究质量,并以质量综合发现.

主要成果:

包括四项研究,209名参与者 (103名在益生菌组). 大多数研究都符合质量标准.
一些研究表明,使用益生菌可以减少焦虑和抑郁,但结果在所有试验中都不一致.
在一项研究中评估了不良事件,显示益生菌和安慰剂组之间没有显著差异.

结论:

目前的证据不足以推益生菌用于纤维肌痛治疗.
需要进一步进行高质量的研究,以确定益生菌在治疗纤维肌痛症状中的作用,并评估其长期安全性.

关键词:

纤维肌痛是一种纤维肌痛.精神障碍精神障碍精神障碍益生菌是一种益生菌.系统性审查系统性审查

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