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Updated: Mar 7, 2026

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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IL-6:在EGFR-TKI抗性瘤微环境中的关键参与者及其治疗影响 (综述)

Qi Wei1, Chengming Huang2, Yuanyuan Zhang1

  • 1Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease‑related Molecular Network, Precision Medicine Center/Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.

International journal of oncology
|March 6, 2026
PubMed
概括

介素-6 (IL-6) 驱动对表皮生长因子受体氨酸激酶抑制剂 (EGFR-TKI) 的耐药性,并抑制非小细胞肺癌 (NSCLC) 的抗瘤免疫力. 阻断IL-6可以克服NSCLC的治疗耐药性.

关键词:
在EGFR-TKI的耐药性方面.在IL-6中,IL-6是最常见的.在NSCLCLC中,我们可以看到NSCLCLC.在TME中,它是最重要的.免疫抑制剂 免疫抑制剂免疫疗法 免疫疗法

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