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急性静脉血栓栓塞症患者的结构化运动训练和康复:随机对照试验的系统审查

Daniel Steiner¹, Moritz Staudacher², Brigitte Wildner³

¹Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

European journal of preventive cardiology

|March 6, 2026

概括

静脉血栓栓塞 (VTE) 后的早期运动训练 (ET) 是安全的,但缺乏有效性的强有力的证据. 需要更多的大规模试验来确认功能和生活质量方面的好处,并预防长期并发症.

科学领域:

心脏病学心脏病学
康复医学康复医学康复医学
运动生理学运动生理学

背景情况:

静脉血栓栓塞 (VTE),包括深静脉血栓塞 (DVT) 和肺栓塞 (PE),可以导致长期的功能限制和降低生活质量.
早期康复,在VTE诊断后3个月内开始的专门结构化的运动训练 (ET),可以减轻这些持续的损伤.
在VTE康复中早期ET的安全性和有效性需要系统评估.

研究的目的:

系统地审查在急性静脉血栓栓塞 (VTE) 的康复中早期启动结构化运动训练 (ET) 计划的安全性和有效性.
评估早期ET对VTE患者的功能结果和生活质量的影响.
确定目前关于VTE康复ET的ET研究中的差距.

主要方法:

在MEDLINE,EMBASE和CENTRAL系统搜索随机对照试验 (RCT),评估在VTE后3个月内启动的结构化ET.
包括将ET与标准治疗进行比较的研究,由两个审查员进行独立查和数据提取.
使用柯克兰偏差风险2工具评估偏差风险.

主要成果:

总共250名患者的4个RCT符合纳入标准.
三项研究表明,ET组内的运动能力,心肺功能或生活质量有所改善,尽管与对照组的差异在统计学上并不显著.
在VTE后3个月内开始的ET没有报告任何安全问题,患者通常能很好地容忍干预措施.

结论:

在VTE之后,早期启动结构化的ET和康复计划似乎是安全的.
目前关于ET对改善VTE患者功能和生活质量的疗效的证据有限.
大规模的RCT是有必要的,以最终评估ET在预防后血栓塞和后PE综合征方面的好处.

关键词:

深静脉血栓形成的原因之一是深静脉血栓.运动训练是运动训练.肺栓塞肺栓塞是一种肺栓塞.随机对照试验是随机对照试验.康复康复康复康复静脉血栓塞栓症是一种静脉血栓塞栓症.

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