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Updated: Mar 8, 2026

Real-time Imaging of Myeloid Cells Dynamics in ApcMin/+ Intestinal Tumors by Spinning Disk Confocal Microscopy
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APC协调SETD8的GSK3酸化以抑制结直肠癌的发生

Zvi Cramer1, Keara Monaghan1, Ricardo Petroni1

  • 1Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Cell reports
|March 6, 2026
PubMed
概括

在结直肠癌 (CRC) 中,APC瘤抑制剂的丧失导致SETD8的瘤活性. 通过GSK3的酸化抑制SETD8,防止基因激活和YAP在CRC中的可访问性.

关键词:
这是APC的APC.CP:癌症的癌症.科普:分子生物学H4K20me1 在线观看在SETD8中,它是SETD8.雅普/河马是什么意思这种蛋白质是β-catenin,也就是β-catenin.结肠直肠癌是什么意思胎儿重编程 胎儿重编程我们的肠道是肠道.有机体有机体是有机的有机物酸化的方法是:光化.

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