相关实验视频
Updated: Mar 8, 2026

13:13
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
14.4K
在没有并发症的怀孕中,羊水胆酸和胆红素的参考范围
Gynecologic and obstetric investigation
|March 6, 2026
概括
在正常怀孕中,确定了羊水胆酸和胆红素的参考值. 在胆汁酸和玛-胺转移酶 (GGT) 之间发现了相关性,这表明了潜在的诊断效用.
科学领域:
- 围产期诊断 围产期诊断 围产期诊断
- 发现生物标志物的发现.
- 孕产妇和胎儿的医学
背景情况:
- 胚胎液分析对于胎儿的健康至关重要.
- 建立生物化学标记物的规范性数据对于诊断解释至关重要.
- 胆酸和胆红素是肝胆功能的关键指标.
研究的目的:
- 为了确定羊水胆汁酸和胆红素的参考范围.
- 调查这些分析物和消化酶之间的相关性.
- 为怀孕中新型诊断方法奠定基础.
主要方法:
- 对133名孕妇 (17-23周怀孕) 的前性横截面研究.
- 胚胎切开术用于采集胚胎液样本.
- 评估胆汁酸,胆红素和各种肝胆酶 (AST,ALT,ALP,LDH,GT) 的水平.
主要成果:
- 对于羊水胆汁酸的确定的参考范围 (第5,第50,第95个百分点:1.3,7.2,30.8微米).
- 胆酸水平与妊娠年龄没有显著变化.
- 在胆汁酸和玛-胺转移酶 (GGT) 之间发现了显著的正相关性.
结论:
- 在怀孕早期到中期,胚胎液胆酸和胆红素的规范值已成功确定.
- 胆酸和GGT之间的相关性表明它们作为补充生物标志物的潜力.
- 这些发现可能有助于诊断胎儿疾病,例如胎儿胆囊的非可视化.
相关概念视频
Serum Studies: Renal Function Tests
548
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
548
Disorders of Acid-Base Balance
2.2K
The human body maintains a precise pH range of arterial blood between 7.35 and 7.45. Deviations result in either acidosis (pH < 7.35) or alkalosis (pH > 7.45). These conditions are further classified as respiratory or metabolic disorders based on their underlying cause.
Respiratory Acidosis and Alkalosis
Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...
Respiratory Acidosis and Alkalosis
Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...
2.2K
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
245
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
245
Bile
5.2K
Bile is a crucial bodily fluid, characterized by its yellow-green color and alkaline nature. Produced in the liver, it is transported through the common hepatic duct into either the cystic duct, leading to the gallbladder, or directly into the common bile duct. The flow of bile is regulated by the sphincter of Oddi located at the entrance of the duodenum. When this sphincter is closed, bile is redirected to the gallbladder for storage and concentration.
Bile is released when dietary fats enter...
Bile is released when dietary fats enter...
5.2K

