分析血液中的重金属与耳之间的关联
XueTong Jin1, ShuRui Si2, ZheZhu Cui1
1Department of Otorhinolaryngology, Head and Neck Surgery, Yanbian University Hospital, Yanji, Jilin Province, China.
Medicine
|March 6, 2026
概括
暴露于和等重金属与更高的耳风险有关. 血液中,,和的含量显示出与耳发病率的显著关联.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 流行病学 流行病学
背景情况:
- 耳是成年人普遍存在的听觉症状.
- 环境污染,特别是重金属,与听力损失有关.
- 重金属和耳之间具体的关系还没有得到充分的研究.
研究的目的:
- 为了研究血中五种重金属 (,,,,,) 和耳之间的关系.
- 探索这些关联中的潜在非线性关系和子组变异.
主要方法:
- 在国家健康和营养检查调查中,对4950名参与者 (2012-2018) 的横截面数据进行分析.
- 使用加权多变量逻辑和线性回归,受限立方线和ROC曲线分析.
- 进行了子组和敏感性分析,以确保调查结果的可靠性.
主要成果:
- 血中和含量较高的四分位数显著与 tinnitus 的几率增加有关.
- 在耳和血液中,,和水平之间观察到非线性关联.
- 关联因性别,种族和年龄而异,在各个子组中显示稳定的关联.
结论:
- 血液中的,,和水平与耳的流行率有显著的相关性.
- 这些金属的含量升高可能是声管理的潜在指标.
- 进一步研究将重金属与耳联系在一起的毒理机制是有必要的.
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