索马里食道癌症:摩加迪沙多中心观察研究的负担和结果
Jamal Saman1, Abdikarim Ibrahim Ali2,3, Hamdi Mohamed Isse4,5
1Institute of Research and Development, Benadir University, Mogadishu, Somalia.
JCO global oncology
|March 6, 2026
概括
食道癌 (EC) 是东非的主要死亡原因. 这项在索马里的研究发现了晚期诊断,有限的治疗选择和低生存率,突出了改善医疗保健基础设施的迫切需要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 食道癌 (EC) 是一个重要的全球健康问题,特别是在东非的高发病率带.
- 索马里缺乏癌症登记册和结果数据,需要对其EC负担进行研究.
研究的目的:
- 调查索马里摩加迪沙的食道癌的负担,临床病理特征,治疗模式,转诊途径和结果.
- 为了在一个流行病学信息有限的地区建立食道癌的基线数据.
主要方法:
- 对468名患者 (≥18岁) 的回顾性审查,其中包括2022年1月至2024年12月期间诊断的经组织学确认的EC患者.
- 数据收集包括来自两个主要诊断中心的人口统计,临床表现,病理学,治疗和转诊信息.
- 对提取的数据进行描述性分析,以描述摩加迪沙的EC景观.
主要成果:
- 食道癌是被诊断的最常见的癌症; 62%的患者是女性,平均年龄为55.9岁.
- 大多数患者出现了晚期疾病 (病期记录不充分),状细胞癌占主导地位 (97.6%).
- 治疗是有限的,单独的化疗是最常见的;手术和化疗是罕见的. 观察到高无治疗率 (21.8%) 和随访损失率 (44.2%),以及低生存率 (40.0%的随访病例死亡率).
结论:
- 这项研究是索马里首次对食道癌的多中心调查,揭示了晚期呈现,分期和治疗的重大差距以及不利的生存结果.
- 对诊断基础设施,多学科护理和癌症登记系统的紧急改进对于改善索马里食道癌患者的治疗结果至关重要.
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