非传染性尿道炎的发生率和患病率:系统性审查和元分析
Aswen Sriranganathan1, Jacob Stasso1, Rafael N Miranda2
1Faculty of Medicine, University of Ottawa, Ontario, Canada.
Retina (Philadelphia, Pa.)
|March 6, 2026
概括
非传染性脑膜炎 (NIU) 在成年人中比儿童更常见. 它的发病率和患病率在患有诸如青少年异常性关节炎 (JIA) 和结性脊髓炎 (AS) 等疾病的患者中较高.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 流行病学 流行病学
背景情况:
- 非传染性脑膜炎 (NIU) 是视力障碍的重要原因之一.
- 了解NIU的流行病学负担对于公共卫生规划和资源分配至关重要.
研究的目的:
- 系统地估计非传染性脑膜炎 (NIU) 的全球发病率和流行率.
- 分析不同年龄组和患有特定并发症的患者的NIU率.
主要方法:
- 在主要的电子数据库 (Ovid Medline,Embase,Scopus) 中进行了全面的系统文献搜索,涵盖了2020年至2025年9月的出版物.
- 关于NIU发病率和患病率的数据被提取并使用随机效应元分析进行聚合,考虑了各种人口和并发症背景.
主要成果:
- 分析包括了106项研究,这些研究来自15172个初始记录.
- 对NIU的综合患病率为成年人每10万人中有131.6人,对于儿科患者每10万人中有27.4人.
- 成年人群的综合发病率为每10万人/年204.4,儿科为每10万人/年16.0.
- 显著更高的NIU发病率和患病率在患有青少年异常性关节炎 (JIA),不分化脊柱关节炎 (SpA),牛皮关节炎 (PsA),化脊柱炎 (AS) 和贝赫特病 (BD) 的个体中观察到.
- 对于JIA,患病率为每1000人129.2例,发病率为每1000人年22.4例.
- 对于脊髓炎,患病率为每1000人中153.5例,发病率为每1000人/年中33.5例.
- 对于PsA,患病率为每1000人中有27.3人,发病率为每1000人/年中有13.1人.
- 对AS和BD的患病率分别为每1000人中的183.5和148.6.
结论:
- 非传染性脑膜炎在成年人群中的发病率和患病率高于儿科人群.
- 特定的自身免疫和炎症性疾病,特别是JIA和AS,与NIU的增加率有关.
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