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在体育炼的背景下,BDNF与前额叶皮层的活动有关

Flaminia Ronca¹, Cian Xu², Ellen Kong¹

¹Institute of Sport, Exercise and Health, Division of Surgery and Interventional Sciences, Faculty of Medical Sciences, University College London, London, United Kingdom.

|March 6, 2026

概括

定期运动通过增加脑衍生神经营养因子 (BDNF) 来促进大脑健康和认知功能. 这项研究发现,运动诱导的BDNF增加与认知任务期间改善的前额叶皮质活动相关.

科学领域:

神经科学是一个神经科学.
运动生理学运动生理学
认知科学认知科学

背景情况:

运动对大脑健康,认知功能和来自大脑的神经营养因子 (BDNF) 水平产生积极影响.
运动诱导的BDNF变化与认知增强之间的确切联系尚不清楚.
BDNF通过新陈代谢,血管,神经传输和突触可塑性支持中枢神经系统.

研究的目的:

研究血BDNF (pBDNF) 和血清BDNF (sBDNF) 运动诱导的变化之间的关系.
为了检查这些BDNF变化和前额叶皮层血液动力学活动在久坐不动的成年人之间的关联.
评估12周骑自行车计划对健身和认知功能的影响.

主要方法:

参与者 (n=23) 被随机分配到运动干预 (12周循环) 或对照组.
V·O2max测试评估了身体健康的变化.
血和血清BDNF水平,执行功能,记忆任务和前额叶皮层活动 (fNIRS) 在干预前和后被测量.

主要成果:

运动组在第12周显示血清BDNF (sBDNF) 显著增加,与V̇O2max改善相关.
静止状态的sBDNF/pBDNF水平没有显著增加.
较高的pBDNF和运动诱导的sBDNF与注意力和抑制任务期间前额叶皮质活动减少相关.

结论:

增加体能增加了急性运动后的BDNF转录.
运动诱导的BDNF可能会在执行任务期间调节神经功能.
这表明了身体活动,BDNF和认知表现之间的联系机制.

关键词:

注意力注意力注意力注意力执行职能执行职能执行职能健身适应适应适应适应记忆记忆记忆记忆记忆神经营养素的神经营养素

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