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Updated: Mar 8, 2026

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阿里尔功能化的单和二子黄素衍生物抑制SARS-CoV-2 Spike:ACE2相互作用

Jeremiah Gabriel G Africa1, Kyra Danielle C Magdato1, Monissa C Paderes1

  • 1Institute of Chemistry, College of Science, University of the Philippines Diliman, Quezon City 1101, Philippines.

Bioorganic & medicinal chemistry letters
|March 6, 2026
PubMed
概括

合成了黄素衍生物,通过阻断S:ACE2相互作用来抑制SARS-CoV-2的进入. 四种新型单基化合物表现出显著的抗病毒活性和有利的安全性,显示出作为治疗剂的潜力.

关键词:
在 COVID-19 疫情中,库尔库明是一种黄素.在S:ACE2相互作用中.这就是SARS-CoV-2病毒.尖蛋白质是一种尖蛋白质.

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