太平洋鱼中共同循环的病原体的影响取决于病毒生命周期特征和传播参数之间的相互作用,突出了病原体动物流行病之间的相互依赖
David James Páez1, Courtney Grady1, Jake Gregg1
1Marrowstone Marine Field Station, Western Fisheries Research Center, US Geological Survey, Nordland, WA, USA.
概括
海洋鱼类疾病,病毒性出血性败血症和病毒性红细胞亡,在流行病期间彼此产生负面影响. 这表明相关的易感性,使野生种群的疾病管理复杂化.
科学领域:
- 海洋生物学 海洋生物学
- 疾病生态学 疾病生态学
- 病原体动态 病原体动态
背景情况:
- 宿主对病原体的易感性在流行病期间可以减少,因为易感个体被移除.
- 共同循环的病原体可能会因相关宿主易感性而相互影响彼此的流行病.
- 在野生海洋生物中没有记录过相互的病效应.
研究的目的:
- 量化病毒性出血性败血症 (VHS) 和太平洋鱼中的病毒性红细胞亡 (VEN) 之间的相互影响.
- 调查共感染病原体之间的宿主易感性相关性.
- 评估传染参数对相互病变影响的影响.
主要方法:
- 太平洋鱼 (Clupea pallasii) 的实地和实验室研究.
- 病毒循环和疾病影响的量化.
- 使用两株病原体模型进行模拟.
主要成果:
- 无论是VHS还是VEN病毒都在太平洋鱼种群中传播.
- 一种病原体的感染会对另一种病原体的病原特征产生负面影响.
- 模拟显示传输参数调节相关敏感性的影响.
结论:
- 在海洋宿主中同时发生的病变表明相互影响,表明相关的易感性.
- 单一海洋疾病的管理可能会无意中加剧共同循环的疾病.
- 提供了一个结合现场,实验和建模方法的框架,以评估互惠的动物病影响.
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