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Updated: Mar 8, 2026

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
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通过转氨酶催化动态动态动态分辨率构建β分支芳香D-氨基酸的简洁结构

Zhenling Liu1, Wei Zhai2, Zhihua Zeng3

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Nature communications
|March 6, 2026
PubMed
概括

这项研究提出了一种高效的生物催化方法,用于使用转氨酶酶合成β分支芳香D-氨基酸. 这些新型氨基酸对药物开发至关重要,并成功地被纳入抗瘤药物中.

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