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人类血细胞外囊泡作为炼模仿,在不使用期间保持骨肌肉可塑性

Alexander M Fliflet1,2, Yanqi Tan3, Takeshi M Barnes1

  • 1Department of Health and Kinesiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.

NPJ microgravity
|March 6, 2026
PubMed
概括

运动中的细胞外囊泡 (ExerVs) 并没有防止在卸载过程中肌肉损失,但通过恢复纤维大小和毛细血管,加速恢复. 这表明ExerVs可以在不使用期间保持骨肌肉健康.

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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