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在患有支气管肺功能障碍的婴儿中使用ECMO:文献综述
John Ibrahim1, Nicholas Carr2, Franscesca Miquel Verges3
1University of Texas Southwestern Medical Center, Dallas, TX, USA. John.ibrahim@utsouthwestern.edu.
概括
身体外膜氧化 (ECMO) 正在被重新考虑在患有严重支气管肺功能障碍 (BPD) 的婴儿身上. 进步可能允许ECMO在某些情况下作为恢复或肺移植的桥梁.
科学领域:
- 新生儿科学 新生儿科学
- 儿科肺病学 儿科肺病学
- 支持心肺血管的支持.
背景情况:
- 支气管肺功能障碍症 (BPD) 是婴儿慢性呼吸衰竭的主要原因.
- 严重的BPD需要长时间的机械通风,导致肺高血压,高发病率和死亡率.
- 从历史上看,体外膜氧化 (ECMO) 排除了患有BPD的婴儿.
研究的目的:
- 重新评估ECMO在治疗严重支气管肺功能障碍 (BPD) 的作用.
- 评估ECMO作为潜在的救援疗法,用于因BPD而导致耐火性呼吸衰竭的婴儿.
- 探索ECMO作为在选择的BPD患者中恢复或肺移植的桥梁.
主要方法:
- 审查新兴报告和ECMO技术的进展.
- 分析最新的抗凝策略和通风管理协议.
- 在BPD中考虑ECMO的患者选择标准.
主要成果:
- 在ECMO技术和管理方面的进步导致对BPD进行重新评估.
- 新出现的证据表明,ECMO可能是严重BPD的可行选择.
- 对于精心挑选的婴儿,ECMO可以作为恢复或肺移植的桥梁.
结论:
- 对于严重的支气管肺功能障碍 (BPD) 病例,越来越多地考虑使用ECMO.
- 仔细选择患者至关重要,考虑到肺高血压,右心室功能和肺恢复潜力.
- 在患有BPD的婴儿中,ECMO提供了耐性呼吸衰竭的潜在救援疗法.
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