通过高ISG表达介导的瘤中的reovirus耐药性:通过JAK/STAT通路调节克服治疗耐药性

Yuxin Yang1,2, Xiaojin Lin1,3, Liang Chen4

  • 1Center for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, Guizhou, China.

Virology journal
|March 6, 2026
PubMed
概括

抗逆转录病毒治疗的瘤细胞表现出更高的干扰素刺激基因 (ISG) 表达. 抑制JAK-STAT通路可以克服这种抗性,提高菌病毒的疗效.

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