患者和公众参与 (PPI) 在孕产妇和新生儿临床试验中的报告:一个探索性审查
Kathleen Hannon1,2, Déirdre Daly3,4, Valerie Smith5,6
1School of Nursing and Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin, D02 T283, Ireland. kahannon@tcd.ie.
在孕产妇和新生儿试验中,患者和公众参与 (PPI) 报告很少,只有14%的研究包括PPI信息. 这次审查发现,随着时间的推移,PPI报告的数量没有增加,这表明需要制定更明确的指导方针.
科学领域:
- 临床试验 临床试验
- 孕产妇健康 孕产妇健康
- 新生儿健康 新生儿健康
- 公共卫生研究 公共卫生研究
背景情况:
- 患者和公众参与 (PPI) 是日益增长的研究重点,但其在研究中的流行程度尚不清楚.
- 了解孕产妇和新生儿临床试验中PPI的频率和类型至关重要.
研究的目的:
- 评估母亲和新生儿临床试验报告中报告的当代患者和公众参与 (PPI) 的频率和类型.
- 为了确定这个研究领域的PPI报告是否随着时间的推移而增加.
主要方法:
- 2017年至2022年间在9个医疗保健期刊上发表的孕产妇和新生儿试验报告的探索性审查.
- 搜索了SCOPUS和期刊档案,寻找符合条件的试验报告及其相关协议.
- 对患者和公众参与 (PPI) 活动的任何信息进行审查的确定的文件.
主要成果:
- 分析了352份试验报告和170个相关协议.
- 只有14% (48项试验) 报告患者和公众参与 (PPI),其中大多数 (42%) 在英国进行.
- 在试验设计 (36个试验),试验期间 (29个试验) 和分析/传播 (20个试验) 中报告了PPI. 没有观察到报告的持续增加.
结论:
- 在孕产妇和新生儿临床试验中,患者和公众参与 (PPI) 报告很少,缺乏深度.
- 在学术期刊中实施PPI报告准则可以改善报告和提高认识.
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