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Updated: Mar 8, 2026

Engineering 'Golden' Fluorescence by Selective Pressure Incorporation of Non-canonical Amino Acids and Protein Analysis by Mass Spectrometry and Fluorescence
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结合,催化和量化:一种现代蛋白质和酶工程工具箱,由基因编码的非正规氨基酸组成

Søren C Spina1, Joe Bailey1, Blaise Kimmel1,2,3

  • 1Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, United States.

Protein engineering, design & selection : PEDS
|March 7, 2026
PubMed
概括

非正规氨基酸 (ncAAs) 扩大了蛋白质工程能力. 最近的进展表明,ncAAs可以增强酶功能,引入新的反应性,并作为实时分子分析的生物物理记者.

关键词:
生物催化剂是一种生物催化剂.生物物理性质表征金属酶是一种金属酶.非正规氨基酸 非正规氨基酸蛋白质工程是指蛋白质工程.

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From DNA to Protein03:06

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The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
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