相关实验视频
Updated: Jul 5, 2026

17:15
Catheterization of Intestinal Loops in Ruminants
Published on: June 11, 2009
14.1K
绵羊和山羊的心脏病变与自发的D型肠毒症
Emma H Torii1, Omar A Gonzales-Viera1, Jennine Ochoa2
1University of California, Davis, Davis, CA.
Veterinary pathology
|March 7, 2026
概括
在19%的羊和山羊中发现了心脏病变,这些羊和山羊患有Clostridium perfringens D型肠毒症. 这些心脏问题,包括退化和出血,可能会导致小反动物的疾病严重程度.
科学领域:
- 兽医病理学 兽医病理学
- 小小的反动物医学
- 传染性疾病 传染性疾病
背景情况:
- 克洛斯特里迪亚透菌类型D肠毒性病是小反动物的一种重大疾病.
- 这种情况中的心脏参与尚未得到广泛的特征.
- 了解心脏病变对于诊断和管理肠毒性病至关重要.
研究的目的:
- 调查羊和山羊患有Clostridium perfringens D型肠毒性病的心脏病变的发生率和性质.
- 为了比较绵羊和山羊之间特定心脏病变的发生率.
- 评估心脏病变在肠毒性病变的潜在作用.
主要方法:
- 对被诊断患有Clostridium perfringens D型肠毒症的病例进行了12年的回顾性分析.
- 从受影响的绵羊和山羊的心脏组织的组织学检查.
- 特定心脏病变的记录和比较,包括退行,亡,出血和.
主要成果:
- 在19% (20/106) 的病例中发现心脏病变.
- 心肌退化/亡发生在80%受影响的动物中,山羊 (100%) 比绵羊 (60%) 更频繁.
- 在85%的病例中观察到出血,在羊 (100%) 比山羊 (70%) 更常见. 在30%的病例中,仅在羊群中观察到蛋白质性间歇性.
结论:
- 心脏病变是小反动物中Clostridium perfringens D型肠毒症自发病例的一个显著发现.
- 具体的病变模式在绵羊和山羊之间有所不同.
- 这些心脏病变可能会导致与肠毒血症相关的临床表现和死亡率.
相关概念视频
Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Hepatitis
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Inflammatory Bowel Disease III: Crohn's Disease
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...

