在患有糖尿病的成年人中,隔膜肌肉衰弱
Charles Frederick Hayfron-Benjamin1, Gifty Aba Tetteh2, Emmanuel Kottoh2
1Department of Physiology, University of Ghana Medical School. P O Box GP 4236, Accra, Ghana; Departments of Internal Medicine, Vascular Medicine, and Public Health, Amsterdam UMC, University of Amsterdam, Cardiovascular Sciences. Meibergdreef 15, 1105AZ Amsterdam, The Netherlands.
隔膜肌肉衰弱 (DMW) 在患有糖尿病的成年人中很常见,甚至在正常螺旋测量时也会影响20%以上. 通过强迫生命能力 (FVC) 的变化来衡量这种情况,表明潜在的健康风险.
科学领域:
- 肺部病理学 肺部病理学
- 内分泌学 在内分泌学.
- 临床医学 临床医学
背景情况:
- 糖尿病与肺部并发症有关,包括肺功能受损.
- 隔膜肌肉衰弱 (DMW) 是不良临床结果的公认预测因素,但在糖尿病人群中尚未研究.
研究的目的:
- 通过使用代用措施来确定糖尿病成年人中DMW的患病率.
- 为了评估DMW和标准螺旋计检测结果在这个队列中的关系.
主要方法:
- 一项涉及537名糖尿病成年人而没有先前存在的肺部疾病的横截面研究.
- 在坐着和躺着的位置进行螺旋测量,以计算强迫生命能力 (∆FVC) 的百分比变化.
- 根据特定的∆FVC切线值 (10-20%) 定义了DMW.
主要成果:
- 根据截止值,DMW的患病率有所不同,仅考虑∆FVC时,从6.1%到20.1%不等.
- 当与预测的减少的FVC%相结合时,DMW患病率在2.6%至9.3%之间.
- 值得注意的是,DMW存在于6.6%至20.7%的精神测量结果正常的个体中.
结论:
- 隔膜肌肉衰弱在患有糖尿病的成年人中很普遍,无论标准的螺旋计结果如何.
- 这些发现凸显了对DMW在糖尿病中的预测因子和临床影响的进一步研究的需要.
- 在糖尿病患者中研究评估DMW的替代方法是有必要的.
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