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Updated: Mar 9, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

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介素-30促进黑色素瘤的扩散,并触发LAG-3表达和T细胞耗尽

Simona Marchetti1, Carlo Sorrentino1, Cristiano Fieni1

  • 1Department of Medicine and Sciences of Aging, "G. d'Annunzio" University" of Chieti-Pescara, Via dei Vestini, Chieti 66100, Italy; Anatomic Pathology and Immuno-Oncology Unit, Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, Via L. Polacchi 11, Chieti 66100, Italy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|March 7, 2026
PubMed
概括

介素30 (IL30) 通过促进癌细胞迁移和T细胞枯竭,驱动黑色素瘤转移和免疫抵抗. 这一发现揭示了IL30作为改善黑色素瘤治疗结果的关键目标.

关键词:
互乐金 - - 30 的作用.淋巴细胞激活 基因3黑色素瘤是一种黑色素瘤.转移驱动基因是转移的驱动基因.T细胞耗尽的情况.

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