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Updated: Mar 9, 2026

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细胞质尾部的多样性决定了粘附GPCRADGRL2的效应因子偏差

Krassimira A Garbett1, Chen Zheng1, Julia Drube2

  • 1Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240, USA.

Cell chemical biology
|March 7, 2026
PubMed
概括

粘附G蛋白结合受体 (aGPCRs) 细胞内尾巴的多样性控制了信号传递. ADGRL2尾巴的替代拼接决定了G蛋白激活和阿雷斯-3结合,揭示了不同的效应因子偏差机制.

关键词:
这是一种G蛋白质蛋白质,G蛋白质蛋白质.在GPCR中,GPCR是指GPCR.格鲁吉亚 格鲁吉亚 格鲁吉亚 格鲁吉亚附着性 GPCRR 的附着性在被逮捕后被捕.拉特罗菲林是一种中毒物质.信号偏差是一种信号偏差.

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