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Updated: Mar 9, 2026

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微血管运输和调节微血管功能编辑的综合实验和理论方法:实验和计算视角

Peter Balogh1, Osama Harraz2

  • 1Department of Mechanical and Industrial Engineering, New Jersey Institute of Technology, Newark, NJ, 07114, USA.

Microvascular research
|March 7, 2026
PubMed
概括

微循环通过血液流动和细胞信号传递不断适应,这对健康和疾病至关重要. 了解这些动态有助于开发各种疾病的治疗方法.

关键词:
计算建模计算建模流量调节器 流量调节器血液动力学 血液动力学微循环是一种微循环.微血管信号传递系统红细胞是血液中的红细胞.

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Physiological pharmacokinetic models, often called flow-limited or perfusion models, typically assume a swift drug distribution between tissue and venous blood, creating a rapid drug equilibrium. This premise is based on the idea that drug diffusion is extremely fast, and the cell membrane presents no barrier to drug permeation. In this scenario, where no drug binding occurs, the drug concentration in the tissue equals that of the venous blood leaving the tissue. This greatly simplifies the...
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