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Updated: Mar 9, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

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剪接,RNA编辑和辅助子单元通过协调进化的过程塑造了AMPA受体功能.

Derek Bowie1

  • 1Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.

Trends in neurosciences
|March 7, 2026
PubMed
概括

AMPA受体 (AMPARs) 的转录后调节涉及拼接和RNA编辑,与TARPs和CNIH等辅助蛋白协调. 这种综合系统扩大了脊椎动物大脑中的刺激信号,与神经疾病相关的干扰.

关键词:
自闭症自闭症是什么iGluR的多元化方式智力障碍 智力障碍是一种智力障碍.离子通道进化过程错误的感觉突变的突变.突触性可塑性 突触性可塑性

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