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Updated: Mar 9, 2026

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在酵母d-阿斯巴达酸氧化酶中的基质特异性的结构引导工程

Sota Zaitsu1, Daiki Imanishi1, Shouji Takahashi1

  • 1Department of Materials Science and Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata 940-2188, Japan.

Journal of bioscience and bioengineering
|March 7, 2026
PubMed
概括

研究人员设计了酵母d-阿斯巴达酸氧化酶 (DDO) 来选择性地检测特定的d-氨基酸. 这一突破使得用于生物标志物开发的复杂混合物中d-histidine或d-phenylalanine的精确量化成为可能.

关键词:
模拟分子动力学模拟基质特异性 基质特异性在d-氨基酸中.d-氨基酸氧化酶的使用.d-阿斯巴酸盐氧化酶的使用d-希斯提丁是一种素.d-氨酸氨酸的使用.

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