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Updated: Mar 9, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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Published on: April 9, 2014

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复发性和新的进化途径在体外驱动HIV-1 lenacapavir耐药性,具有多样化的表型后果

Luke L Orris1, Mohammad Adnan Siddiqui1, Junyi Tang1

  • 1Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Nature communications
|March 7, 2026
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 可以通过突变对莱纳卡帕维尔 (LEN) 囊抑制剂产生耐药性. 新的抗药性途径增强了病毒的健康状况,并可能为未来的药物开发提供信息.

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