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Updated: Mar 9, 2026

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在癌症治疗中准SETD2:结构,生物功能和抑制剂开发

Peng Wang1, Yonghui Chang1, Fei Ding1

  • 1Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, China.

Bioorganic chemistry
|March 8, 2026
PubMed
概括

含有SET域的蛋白2 (SETD2) 对于基因组稳定性和DNA修复至关重要. 在SETD2突变促进癌症,使其成为一个关键的治疗目标.

关键词:
H3K36me3是什么意思 H3K36me3是什么意思抑制剂是一种抑制剂.甲基英多尔核的核.这是一种S-adenosylmethionine类型的类似物.这就是SETD2的原因.结构与活动之间的关系.

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