达科尼亚劳拉维 (法语) 施耐德聚醇:优化超声波辅助提取和生物活性研究
Tingting Zhang1, Liguo Yang2, Fan Xie3
1Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Ultrasonics sonochemistry
|March 8, 2026
概括
使用超声波辅助提取 (UAE) 有效地提取了Docynia delavayi多 (DDP). DDP表现出强大的抗氧化剂,酶抑制剂和抗微生物特性,可能作为改善肠道健康的益生菌.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 微生物学 微生物学
背景情况:
- 中国植物Docynia delavayi富含多,具有传统医疗用途.
- 德拉瓦伊多 (DDP) 的生物活性在很大程度上仍未得到研究.
- 需要有效的提取和DDP的全面生物活性评估.
研究的目的:
- 为优化D. delavayi多 (DDP) 的超声波辅助提取 (UAE).
- 系统地评估DDP的体外生物活性,包括抗氧化剂,酶抑制和抗菌作用.
- 研究DDP对肠道微生物群组成和宿主新陈代谢的影响.
主要方法:
- 超声辅助提取 (UAE) 通过单因子测定和响应表面方法来优化.
- 在体外测定抗氧化活性 (DPPH),碳水化合物消化酶抑制 (α-葡萄糖酶,α-氨酶) 和抗菌活性.
- 甲基因组和非目标代谢学分析,以评估肠道微生物群和代谢概况.
主要成果:
- 阿联的最佳条件:43%的乙醇,460W,21毫升/克,41分钟.
- DDP显示出强大的抗氧化剂 (IC50 = 3.75μg/mL),α-葡萄糖酶和α-氨酶抑制活性.
- DDP抑制了致病细菌 (大肠杆菌,B. subtilis,S. aureus,沙门氏菌) 和调节了肠道微生物群,促进了有益的细菌和减少了病原体.
- DDP丰富了与肠道中的脂肪酸代谢相关的途径.
结论:
- 为DDP建立了一个有效的阿联方法.
- DDP具有显著的抗氧化剂,酶抑制剂,抗微生物和类似益生菌的特性.
- DDP调节肠道微生物群和新陈代谢,表明改善宿主健康和高价值利用的潜力.
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