相关实验视频

Updated: Mar 9, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

11.9K

设计,合成和新型单糖TLR4激动剂的免疫学评估

Zhi-Ming Zhang1, Yu Wen1, Meng-Qiang Luo1

  • 1National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.

Bioorganic chemistry
|March 8, 2026
PubMed
概括

基于葡萄糖胺的4-酸盐 (GAP) 化合物提供了一个更简单的替代方案,可以作为疫苗辅助剂使用单酸脂A (MPLA). GAP类似物有效地激活托尔类受体4 (TLR4),其中GAP214显示出优异的免疫反应.

关键词:
免疫刺激剂 免疫刺激剂脂质A类类似物在MPLA中,MPLA就是一个MPLA.这是一种TLR4激动剂.疫苗辅助剂是疫苗的辅助剂.

更多相关视频

A Simple and Efficient Method for Testing Immunomodulatory Agents for Generation of Tolerogenic Dendritic Cells from Human CD14+ Monocytes11:34

A Simple and Efficient Method for Testing Immunomodulatory Agents for Generation of Tolerogenic Dendritic Cells from Human CD14+ Monocytes

Published on: April 11, 2025

908
Detection of Neu1 Sialidase Activity in Regulating TOLL-like Receptor Activation09:04

Detection of Neu1 Sialidase Activity in Regulating TOLL-like Receptor Activation

Published on: September 7, 2010

12.0K

相关概念视频

Formation of Lipopolysaccharides01:19

Formation of Lipopolysaccharides

Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin,...
816