临床过程和患者报告的结果在保守管理的脊髓洞腔形缺陷中
Abel Clemens Adriaan Sandmann1,2, Marinus Abraham Kempeneers2,3, K Mariam Slot2,3
1Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Journal of neurology
|March 8, 2026
概括
对于大多数患者来说,脊柱洞性形 (SCM) 的保守管理是有效的,保持功能独立. 然而,保守治疗的SCM患者报告与一般人群相比,与健康有关的生活质量较差.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 临床结果研究研究
背景情况:
- 脊柱洞性形 (SCM) 是一种罕见的血管病变.
- 关于SCM保守管理结果的数据有限.
- 评估临床和患者报告的结果对于SCM管理策略至关重要.
研究的目的:
- 为了评估SCM患者的临床和功能结果,保守地管理.
- 为了评估患者报告的生活质量和精神健康在这个队列.
- 在保守管理的SCM中确定症状出血或神经缺陷的发生率.
主要方法:
- 在保守管理下对成年SCM患者 (1995-2024) 进行单中心队列研究.
- 对症状性出血 (SH) 和焦点神经缺陷 (FND) 的回顾性分析.
- 使用问卷 (mRS,EQ-5D-5L,PROMIS-29) 进行功能和生活质量评估.
主要成果:
- 包括28名SCM患者;36%的患者呈现SH/FND.
- 随访时间中位数为6.4年;36%的患者经历了SH/FND,18%的患者需要手术.
- 在随访时,93%的人完成了问卷,57%的人在功能上是独立的 (mRS ≤ 2),EQ-5D-5L得分较低,PROMIS-29焦虑,抑郁和疲劳更高.
结论:
- 对大多数SCM患者来说,保守的治疗是可行的选择,82%的患者避免了手术.
- 大多数保守管理的SCM患者保持功能独立.
- 与普通人群相比,SCM患者报告与健康相关的生活质量明显差,特别是心理健康.
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