肌肉强度与腹部大动脉化相关联
Xiao-Xue Li1, Feng-Shun Wang1, Hao Wang1
1Department of Cardiology, Mudanjiang Cardiovascular Hospital, China.
The Journal of international medical research
|March 8, 2026
概括
较高的握力与男性和女性下腹大动脉化风险有关. 这种关联是独立的和剂量依赖的,表明肌肉力量是血管健康的关键指标.
科学领域:
- 心血管健康 心血管健康
- 肌肉骨健康 肌肉骨健康
- 老年学是指老年学的学科.
背景情况:
- 腹腔大动脉化 (AAC) 是动脉样硬化的标志物,与肌肉骨衰退共享路径.
- 握力预测心血管结果,但其与AAC的性别特异性联系尚未得到充分研究.
研究的目的:
- 为了研究抓握力和腹腔大动脉化之间的性别特定关联.
- 探索剂量-反应关系和各个子组的一致性.
主要方法:
- 从2013-2014年NHANES中对1683名成年人的横截面分析.
- 用双能X射线吸收度量化AAC (Kauppila分数);用动力计测量握力.
- 性别特定的多变量逻辑回归和受限制的立方线分析了关联.
主要成果:
- 在男性 (OR 0.982) 和女性 (OR 0.974) 中,每增加1公斤的握力与AAC风险降低相关.
- 观察到线性反向的剂量反应关系 (p < 0.05).
- 关联在年龄,BMI,高血压和糖尿病亚组中保持一致.
结论:
- 按握力评估的肌肉强度与AAC患病率独立且反向相关.
- 握力作为AAC风险分层的实用生物标志物.
- 改善肌肉骨健康可能有助于预防血管化.
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