更狭窄的球球及其支流与骨基静脉高强度有关,在动脉旋转标记MRI上
Periakaruppan V Manickam1, Yusef Qazi2, Siddhant Suri Dhawan1
1Division of Neuroimaging and Neurointervention, Department of Radiology, Stanford Center for Academic Medicine, Radiology MC: 5659, Stanford University School of Medicine, Radiology MC: 5659, 453 Quarry Road, Stanford, CA, 94304, USA.
Scientific reports
|March 9, 2026
概括
较小的球球和后状静脉大小与偶尔的动脉旋转标记MRI高强度 (ASL+) 有关. 这一发现有助于解释一种常见的成像陷,该陷可以模仿其他条件.
科学领域:
- 血管成像 血管成像
- 神经成像是一种神经成像.
- 放射学 放射学是一门学科.
背景情况:
- 偶然的动脉旋转标记在球球 (JB) 的MRI高强度 (ASL+) 可能会被误认为是长期动脉静脉.
- 这种ASL+发现的解剖学基础尚未完全理解,这可能导致误诊.
- 了解与ASL+相关的静脉解剖学对于精确解释神经成像研究至关重要.
研究的目的:
- 调查球 (JB) 与其支流静脉大小之间的关联以及ASL+的存在.
- 确定特定的静脉形态学模式是否有助于ASL+的发生.
- 根据静脉解剖学来区分ASL+和其他血管异常.
主要方法:
- 从25名ASL+患者和25名对照患者的MRI回顾分析.
- 使用对比后的SPGR图像测量球球 (JB) 和后状静脉 (PCV) 的直径.
- 统计分析包括组比较,效果大小,FDR校正,ROC分析和LOOCV用于模型验证.
主要成果:
- 与对照组相比,ASL+患者的JB中部,JB外流和PCV直径显着较小.
- 在FDR调整后,只有较小的PCV直径仍然具有统计学意义.
- 接收器操作特征 (ROC) 分析表明,对JB措施的中度歧视 (AUC ≈ 0.67) 和PCV的更强的歧视 (AUC = 0.78);一个多变量模型实现了AUC = 0.83.
结论:
- 以较小的JB和PCV口径为特征的静脉形态图案与ASL+有关.
- 这种解剖结构可能导致延迟静脉通行和信号捕获,导致ASL+成像陷.
- 这些发现表明ASL+的探索性结构基础,并要求对其机制基础进行进一步调查.
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