食品级TiO2/TDCPP同时暴露破坏了ACOD1/伊塔康酸轴,与微质中TET2-NF-κB炎症有关,恶化神经毒性

Qing Guo1, Duijuan Wang1, Changning Zhao1

  • 1Center for Environment and Health in Water Source Area of South-to-North Water Diversion, School of Public Health, Hubei University of Medicine, Shiyan 442000, China; Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei University of Medicine, Shiyan 442000, China.

概括

食品级二氧化 (TiO2) 和TDCPP暴露会损害儿童的神经发育. 联合暴露激活了微质,导致神经元亡和炎症,表明伊塔科纳酸作为一种潜在的治疗方法.

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