手术前系统性免疫炎症指数与距离动脉静脉囊失败独立相关
Bedirhan Buğra Bayıcı1, Fatih Kızılyel1
1Department of Cardiovascular Surgery, Koşuyolu High Specialization Training and Research Hospital, Istanbul, Türkiye.
Annals of vascular surgery
|March 9, 2026
概括
通过全身免疫炎症指数 (SII) 测量系统性炎症,可以独立预测远端动脉静脉 (AVF) 衰竭,即使有合适的解剖学. 术前SII可以在AVF规划和解剖评估中提供帮助.
科学领域:
- 血管外科 血管外科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 炎症研究 炎症研究
背景情况:
- 远端动脉静脉囊 (AVF) 衰竭是一个重大的临床挑战,影响了血液透析的准入.
- 仅仅对血管解剖学的术前评估可能无法完全预测AVF的成功.
- 系统性炎症越来越多地被认为是外科手术结果的一个因素.
研究的目的:
- 评估手术前系统性免疫炎症指数 (SII) 和远端AVF衰竭之间的关联.
- 在调整了解剖学和临床因素后,确定SII是否是AVF失败的独立预测因素.
主要方法:
- 对209名接受远程AVF创建的患者进行了回顾性单中心研究.
- 通过双重超声波测定术前血管解剖学.
- 使用SII评估系统性炎症状态;进行后勤回归分析以预测结果.
主要成果:
- 距离AVF衰竭发生在19.6%的患者中.
- 多变量分析显示,较小的远距离静脉直径和较高的手术前SII独立地与增加的AVF失败风险有关.
- 晚年与AVF衰竭的可能性较低有关.
结论:
- 手术前的SII是在解剖学上选择的队列中,是远程AVF失败的独立预测因素.
- 有利的血管解剖学仍然是AVF结果的最强决定因素.
- 在AVF规划中,SII可以作为一种有价值的补充工具,用于风险分层.
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