在开始高剂量西马格卢提德后同时出现双边NAION:一个病例报告
V M Asensio-Sánchez1, J Rodríguez-Espinosa1, S Silva-Schultz1
1Servicio de Oftalmología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Archivos de la Sociedad Espanola de Oftalmologia
|March 9, 2026
概括
一个罕见的双边同时发生的非动脉炎前面缺血性视神经病变 (NAION) 发生在一个患者接受治疗的semaglutide. 这凸显了需要仔细监测糖尿病患者GLP-1受体激素治疗的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 神经学 神经学
背景情况:
- 非动脉炎前面缺血性视神经病变 (NAION) 是视神经损伤的主要原因.
- 2型糖尿病和解剖学风险因素,如拥挤的光盘增加了NAION风险.
- GLP-1受体激动剂越来越多地用于2型糖尿病管理.
研究的目的:
- 报告一个独特的案例,在开始服用西马格卢提德后同时出现双边NAION.
- 讨论对临床实践的潜在关联和影响.
主要方法:
- 一个68岁的男性患有2型糖尿病和视障病例报告.
- 眼科检查,包括 funduscopy 和视力敏度的评估.
- 对病史,药物使用 (西马格卢提德) 和实验室结果的审查.
主要成果:
- 患者在两只眼睛中出现了快速,严重的视力损失 (功能性失明).
- 眼科发现包括双边光盘,出血,液和下液.
- 尽管停止治疗和使用皮质类固醇,视力损失仍然存在.
结论:
- 观察到高剂量西马格卢提德启动和同时双边NAION之间的时间关联.
- 易患病的因素包括糖尿病,视力过高和光盘拥挤.
- 强调了基线眼科评估和GLP-1受体激动剂的谨慎剂量的重要性.
关键词:
它是GLP-1受体激动剂.有不良影响的负面影响.它是一种GLP-1激活剂.这是双边双边的.这将产生不利的效果.视觉神经病变是前部没有动脉的.非动脉炎前侧缺血性视神经病变一个半粘性质的半粘性质.塞马格卢提德 (semaglutide) 是一种可怕的药物.更多相关视频
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