产前压力暴露时间预测婴儿交感神经系统和情感反应
Cecilia Martinez-Torteya1, Amy K Nuttall2, G Anne Bogat3
1Department of Psychiatry, University of Michigan - Michigan Medicine, Ann Arbor, Michigan, USA.
Developmental psychobiology
|March 9, 2026
概括
产前压力时间影响婴儿的压力反应,特定的妊娠期会影响交感神经系统活动 (唾液α氨基酶) 和情绪反应 (恐惧,愤怒) 在男孩和女孩之间不同.
科学领域:
- 发展心理学 发展心理学
- 神经科学是一个神经科学.
- 孕产妇健康 孕产妇健康
背景情况:
- 产前压力会对神经发育产生负面影响.
- 特定的妊娠期可能代表这些影响的敏感窗口.
- 了解这些窗口对于减轻长期后果至关重要.
研究的目的:
- 调查产前压力时间,水平和波动对婴儿交感神经系统活动和情绪反应的影响.
- 探索产前压力影响的性别特异性差异.
- 为了识别怀孕期间的敏感时期对产前压力暴露的敏感期.
主要方法:
- 评估了来自多元化,经济弱势社区的195个母婴二合体.
- 从母亲 (怀孕14周到分娩) 收集每周感知压力数据.
- 利用机器学习分析婴儿唾液α氨酶 (sAA),产后6个月的恐惧和愤怒反应,以及压力任务的行为编码.
主要成果:
- 在第三季度早期 (31-32周) 增加的压力预测了更高的SAA和恐惧反应.
- 在怀孕中期 (21周) 和晚期 (38周) 增加的压力预测了更低的愤怒反应.
- 对于产前压力影响的敏感期在男婴和女婴之间有所不同.
结论:
- 关于产前压力时间的细粒度数据对于识别关键发育时期至关重要.
- 评估婴儿生物行为反应性的多种指标,可以全面了解产前压力影响.
- 这些发现强调了在产前压力研究和干预中需要对性别进行特定考虑的必要性.
更多相关视频
04:20Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
2.8K
08:22Measuring Cardiac Autonomic Nervous System ANS Activity in Toddlers - Resting and Developmental Challenges
Published on: February 25, 2016
16.0K
相关概念视频
Physiological Foundation of Stress
860
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Role of the Sympathetic Nervous System
Adrenaline triggers the...
860
Psychological Responses to Stress
806
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
806
Socioemotional Development during Infancy
1.0K
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Primary Temperament Types
1.0K
Introduction to Stress and Lifestyle
735
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
735
Stress and Mental Health
1.1K
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
1.1K
Hypothalamic-Pituitary Axis
69.0K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
69.0K
