内部医学中患者报告的结果:有效的测量和解释的方法考虑
Carmine Zoccali1,2,3, Giovanni Tripepi4
1Renal Research Institute, New York, New York, USA.
European journal of clinical investigation
|March 9, 2026
概括
患者报告的结果测量 (PROM) 在内部医学中至关重要,以超越传统指标来捕捉患者的体验. 本综述详细介绍了开发和使用PROM的最佳实践,以确保它们反映患者的优先事项并改善护理.
科学领域:
- 内部医学 内部医学
- 健康 结果 研究 研究 结果
- 以患者为中心的护理
背景情况:
- 传统的生物医学终点对于慢性多系统性疾病是不够的.
- 患者报告的结果措施 (PROMs) 捕捉症状负担,功能,幸福感和生活质量.
- PROM越来越多地用于监管评估,健康技术评估和基于价值的护理.
研究的目的:
- 概述有效PROM开发,验证和解释的关键概念和实践问题.
- 强调PROM方法学的最佳实践,包括概念框架,项目生成,缩放和心理测量评估.
- 应对异质人群中的挑战,跨文化适应和融入临床实践.
主要方法:
- 在患者报告结果测量发展和验证方面,对文献和最佳实践的审查.
- 强调概念框架,定性研究和心理测量属性 (可靠性,有效性,响应性,可解释性).
- 讨论跨文化适应,差异性物品功能,纵向测量以及整合到临床试验和常规护理中.
主要成果:
- PROMs提供了治疗效益的全面视图,补充了生物医学数据.
- 严格的方法对于PROMs产生有效,可解释和临床上有意义的信息至关重要.
- 解决概念框架,心理测量属性和实施挑战等问题对于有效使用PROM至关重要.
结论:
- 坚持方法论基础确保PROM准确反映患者的经验和优先事项.
- 有效地实施PROM支持以患者为中心的内科.
- 本综述旨在指导临床医生,研究人员和决策者选择和解释PROM.
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