相关实验视频
Updated: Mar 10, 2026
05:34
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
1.9K
亚洲慢性病:一个元分析
Guozhen Chen1, Shirui Sun2, Yingcong Guo2
1Organ Procurement and Allocation Organization, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Kidney research and clinical practice
|March 9, 2026
概括
慢性病 (CKD) 影响亚洲人的17%,在老年人中患病率更高,在不同地区的患病率不同. 年龄和性别显著影响CKD的发病率,需要量身定制的评估.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 慢性病 (CKD) 构成了全球健康的重大负担.
- 了解不同亚洲人群中CKD患病率对于有针对性的干预至关重要.
- 诊断标准和人口因素的变化可能会影响报告的CKD患病率.
研究的目的:
- 确定亚洲1-5期和3-5期CKD的总体流行率.
- 根据年龄,性别,地理区域和分析方法分析CKD患病率的变化.
- 为了比较不同亚洲国家和亚洲次区域的CKD患病率.
主要方法:
- 一项对42项涉及2,271,169名参与者的研究进行了系统的元分析.
- 从五个数据库搜索到2025年2月30日的数据.
- 分析包括1-5和3-5阶段的CKD年龄标准化和性别标准化患病率.
主要成果:
- 在亚洲,CKD第1-5期的总体患病率为17.0%,第3-5期患病率为7.7%.
- 60岁以上的个人表现出比年轻人更高的CKD患病率.
- 观察到显著的地理差异,尼泊尔和南亚的年龄标准化患病率 (aCKD) 1-5最高,越南最低. 伊朗和斯里兰卡的性别标准化患病率最高 3-5.
结论:
- 亚洲的CKD患病率很大,并且因年龄,性别和地区而异.
- 年龄和性别是影响CKD患病率的关键因素,评估必须考虑到这些人口统计数据.
- 在使用CKD流行病学协作和MDRD方法的研究中,发现了患病率的差异.
相关概念视频
01:25Chronic Kidney Disease I: Introduction
928
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
928
01:28Chronic Kidney Disease III: Interprofessional Care
563
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
563
01:24Chronic Kidney Disease II: Clinical Manifestations
860
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
860
01:28Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
285
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
285
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
434
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
434
01:18Chronic Kidney Disease IV: Nursing Management
516
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
516